The use of cabergoline does not influence the pregnancy outcome clinical pregnancy rate, miscarriage rate. Thus large, well-designed and well-executed RCTs that involve more clinical endpoints are necessary to evaluate the role of cabergoline in OHSS prevention. Cabergoline for preventing ovarian hyperstimulation syndrome. Cochrane Database Syst Rev. Resource Centers. Jump to Your Week of Pregnancy.
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Selection criteria: RCTs which compared cabergoline with placebo, no treatment or another intervention for preventing OHSS in high-risk women were considered for inclusion.
Primary outcome measures included incidence of moderate or severe OHSS and live birth rate. Secondary endpoints were clinical pregnancy rate, multiple pregnancy rate, miscarriage rate and any other adverse effects of the treatment.
Data collection and analysis: Two authors independently screened titles, abstracts and the full text of publications; extracted data; and assessed risk of bias. Any disagreements were resolved by consensus.
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